nib Malate
≥99% | 341031-54-7 | 100mg,500mg,1g | 无细胞 | VEGFR2 (Flk-1) | 80 nM | | | | PDGFRβ | 2 nM | | |
| L125046 | Lenalidomide | ≥99% | 191732-72-6 | 50mg,250mg,1g,5g | PBMCs | TNF-α | 13 nM | | |
| C126195 | Cabozantinib (XL184, BMS-907351) | ≥98% | 849217-68-1 | 5mg,10mg,50mg,100mg,250mg | 无细胞 | VEGFR2 | 0.035 nM | | |
| c-Met | 1.3 nM | | |
| Ret | 4 nM | | |
| Kit | 4.6 nM | | |
| Flt-1/3/4 | 12 nM/11.3 nM/6 nM | | |
| Tie2 | 14.3 nM | | |
| AXL | 7 nM | | |
| P127550 | Ponatinib (AP24534) | ≥99% | 943319-70-8 | 10mg,50mg,250mg | 无细胞 | Abl | 0.37 nM | | |
| PDGFRα | 1.1 nM | | |
| VEGFR2 | 1.5 nM | | |
| FGFR1 | 2.2 nM | | |
| Src | 5.4 nM | | |
| K125585 | Ki20227 | ≥98% | 623142-96-1 | 10mg,50mg | | KDR | 2 nM | | |
| VEGFR-2 | 12 nM | | |
| c-Kit | 451 nM | | |
| PDGFRβ | 217 nM | | |
| A129732 | Axitinib | ≥99% | 319460-85-0 | 10mg,50mg,250mg,1g | 猪主动脉内皮细胞 | VEGFR1 | 0.1 nM | | |
| VEGFR2 | 0.2 nM | | |
| VEGFR3 | 0.1-0.3 nM | | |
| PDGFRβ | 1.6 nM | | |
| c-Kit | 1.7 nM | | |
| F127011 | Foretinib (GSK1363089) | ≥98% | 849217-64-7 | 5mg,25mg,100mg | 无细胞 | Met | 0.4 nM | | |
| KDR | 0.9 nM | | |
| N129725 | Nintedanib (BIBF 1120) | ≥98% | 656247-17-5 | 5mg,10mg,25mg,50mg,100mg,500mg | 无细胞 | VEGFR1 | 34 nM | | |
| VEGFR2 | 13 nM | | |
| VEGFR3 | 13 nM | | |
| FGFR1 | 69 nM | | |
| FGFR2 | 37 nM | | |
| FGFR3 | 108 nM | | |
| PDGFRα | 59 nM | | |
| PDGFRβ | 65 nM | | |
| V125180 | Vandetanib (ZD6474) | ≥99% | 443913-73-3 | 25mg,100mg,500mg | 无细胞 | VEGFR2 | 40 nM | | |
| VEGFR3 | 110 nM | | |
| EGFR | 500 nM | | |
| R127804 | Regorafenib (BAY 73-4506) | ≥99% | 755037-03-7 | 5mg,10mg,25mg,100mg | 无细胞 | VEGFR1 | 13 nM | | |
| VEGFR2 | 4.2 nM | | |
| VEGFR3 | 46 nM | | |
| PDGFR-β | 22 nM | | |
| Kit | 7 nM | | |
| RET | 1.5 nM | | |
| Raf-1 | 2.5 nM | | |
| P129722 | Pazopanib HCl (GW786034 HCl) | ≥98% | 635702-64-6 | 25mg,100mg,250mg,1g | 无细胞 | VEGFR1 | 10 nM | | |
| VEGFR2 | 30 nM | | |
| VEGFR3 | 47 nM | | |
| PDGFR | 84 nM | | |
| FGFR | 74 nM | | |
| c-Kit | 140 nM | | |
| c-fms | 146 nM | | |
| C125911 | Cediranib | ≥98% | 288383-20-0 | 10mg,50mg | | VEGFR(KDR) | <1 nM | | |
| Flt1/4 | 5 nM/≤3 nM | | |
| P125865 | PD173074 | ≥99% | 219580-11-7 | 5mg,10mg,50mg | | FGFR1 | 25 nM | | |
| VEGFR2 | 100-200 nM | | |
| D126778 | Dovitinib (TKI-258, CHIR-258) | ≥99% | 405169-16-6 | 10mg,50mg,250mg | 无细胞 | FLT3 | 1 nM | | |
| c-Kit | 2 nM | | |
| L126993 | Linifanib (ABT-869) | ≥99% | 796967-16-3 | 5mg,10mg,50mg | | KDR | 4 nM | | |
| CSF-1R | 3 nM | | |
| Flt-1/3 | 3 nM/4 nM | | |
| PDGFRβ | 66 nM | | |
| V125857 | Vatalanib (PTK787) 2HCl | ≥99% | 212141-51-0 | 10mg,50mg | 无细胞 | VEGFR2/KDR | 37 nM | | |
| R127906 | RAF265 (CHIR-265) | ≥98% | 927880-90-8 | 1mg,5mg,10mg,50mg | | VEGFR2 | | 30 nM | |
| B-Raf | 3-60 nM | | |
| T126012 | Tivozanib (AV-951) | ≥98% | 475108-18-0 | 5mg,25mg,100mg | | VEGFR1 | 0.21 nM | | |
| VEGFR2 | 0.16 nM | | |
| VEGFR3 | 0.24 nM | | |
| M129736 | Motesanib Diphosphate (AMG-706) | ≥98% | 857876-30-3 | 5mg,10mg,50mg | | VEGFR1 | 2 nM | | |
| VEGFR2 | 3 nM | | |
| VEGFR3 | 6 nM | | |
| L125518 | Lenvatinib (E7080) | ≥99% | 417716-92-8 | 5mg,10mg,50mg,100mg | | VEGFR2(KDR) | 4 nM | | |
| VEGFR3(Flt-4) | 5.2 nM | | |
| B127317 | Brivanib (BMS-540215) | ≥98% | 649735-46-6 | 5mg,10mg,50mg | | VEGFR2 | 25 nM | | |
| M127064 | MGCD-265 | ≥98% | 875337-44-3 | 1mg,5mg,10mg,50mg | | c-Met | 1 nM | | |
| VEGFR1/2/3 | 3 nM/3 nM/4 nM | |
| A126830 | AEE788 (NVP-AEE788) | ≥97% | 497839-62-0 | 5mg,25mg,100mg | | EGFR | 2 nM | | |
| HER2/ErbB2 | 6 nM | | |
| E126318 | ENMD-2076 | ≥99% | 934353-76-1 | 5mg,10mg,50mg | | Aurora A | 14 nM | | |
| Flt3 | 1.86 nM | | |
| O126155 | OSI-930 | ≥99% | 728033-96-3 | 1mg,5mg,25mg,50mg | | Kit | 80 nM | | |
| KDR | 9 nM | | |
| CSF-1R | 15 nM | | |
| C126929 | CYC116 | ≥99% | 693228-63-6 | 1mg,10mg,50mg | | Aurora A | | | 8.0 nM |
| Aurora B | | | 9.2 nM |
| VEGFR2 | | | 44 nM |
| K125876 | Ki8751 | ≥98% | 228559-41-9 | 5mg,25mg,100mg | | VEGFR2 | 0.9 nM | | |
| T129747 | Telatinib | ≥99% | 332012-40-5 | 1mg,5mg,10mg,50mg | | VEGFR2/3 | 6 nM/4 nM | | |
| c-Kit | 1 nM | | |
| PDGFRα | 15 nM | | |
| P126419 | PP121 | ≥98% | 1092788-83-4 | 10mg,50mg | | PDGFR | 2 nM | | |
| Hck | 8 nM | | |
| mTOR | 10 nM | | |
| VEGFR2 | 12 nM | | |
| Src | 14 nM | | |
| Abl | 18 nM | | |
| DNA-PK | 60 nM | | |
| P125184 | Pazopanib | ≥99% | 444731-52-6 | 25mg,100mg,500mg | | GFR1 | 10 nM | | |
| VEGFR2 | 30 nM | | |
| VEGFR3 | 47 nM | | |
| PDGFR | 84 nM | | |
| FGFR | 74 nM | | |
| c-Kit | 140 nM | | |
| c-Fms/CSF1R | 146 nM | | |
| K125907 | KRN-633 | ≥97% | 286370-15-8 | 5mg,25mg,100mg | | VEGFR1 | 170 nM | | |
| VEGFR2 | 160 nM | | |
| VEGFR3 | 125 nM | | |
| S126571 | SAR131675 | ≥99% | 1433953-83-3 | 1mg,10mg,50mg | | VEGFR3 | 23 nM | | 12 nM |
| B129768 | BMS-794833 | ≥99% | 1174046-72-0 | 1mg,5mg,10mg,50mg | | Met | 1.7 nM | | |
| VEGFR2 | 15 nM | | |
| S125098 | Sorafenib | ≥99% | 284461-73-0 | 250mg,1g | 无细胞 | Raf-1 | 6 nM | | |
| B-Raf | 22 nM | | |
|
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