CD8A/CD8B monoclonal antibody, clone RFT-8 (PE/TXRD)
产品名称： CD8A/CD8B monoclonal antibody, clone RFT-8 (PE/TXRD)
英文名称： CD8A/CD8B monoclonal antibody, clone RFT-8 (PE/TXRD)
产品编号： MAB6024
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD8A/CD8B.
- Immunogen:
- Native purified from human thymocytes and E-rosetted lymphocytes.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Specificity human CD8
- Form:
- Liquid
- Conjugation:
- PE/TXRD
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (1 mg/mL sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10 ul/106 cells)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The CD8 coreceptor revisited: one chain good, two chains better.
Zamoyska R.Immunity. 1994 Jul;1(4):243-6.
- Application Image
- Immunohistochemistry (Frozen sections)
- Flow Cytometry
- Entrez GeneID:
- 925
- Gene Name:
- CD8A
- Gene Alias:
- CD8,Leu2,MAL,p32
- Gene Description:
- CD8a molecule
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD8 antigen alpha polypeptide,CD8 antigen, alpha polypeptide (p32),Leu2 T-lymphocyte antigen,OKT8 T-cell antigen,T cell co-receptor,T-cell antigen Leu2,T-cell surface glycoprotein CD8 alpha chain,T-lymphocyte differentiation antigen T8/Leu-2,T8 T-cell ant
- Entrez GeneID:
- 926
- Gene Name:
- CD8B
- Gene Alias:
- CD8B1,LYT3,Leu2,Ly3,MGC119115
- Gene Description:
- CD8b molecule
- Omim ID:
- 186730
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq
- Other Designations:
- CD8 antigen, beta polypeptide (p37),CD8 antigen, beta polypeptide 1 (p37),CD8b antigen,OTTHUMP00000160761,T lymphocyte surface glycoprotein beta chain,T-cell surface glycoprotein CD8 beta chain