FITC标记的ISLR2蛋白抗体
产品名称： FITC标记的ISLR2蛋白抗体
英文名称： Anti-ISLR2/FITC
产品编号： HZ-9025R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
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- 邮编 : 200612
- 所在区域 : 上海
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Rabbit Anti-ISLR2/FITC Conjugated antibody
FITC标记的ISLR2蛋白抗体
| 产品编号 | bs-9025R-FITC |
| 英文名称 | Anti-ISLR2/FITC |
| 中文名称 | FITC标记的ISLR2蛋白抗体 |
| 别 名 | Immunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein; ISLR2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 77kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ISLR2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1. Function: Required for axon extension during neural development (By similarity). Subunit: Homomultimer. Interacts with NTRK1/TrkA (By similarity). Subcellular Location: Cell membrane; Single-pass membrane protein (By similarity). Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Contains 5 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: Entrez Gene: 57611 Human Entrez Gene: 320563 Mouse SwissProt: Q6UXK2 Human SwissProt: Q5RKR3 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
富含亮氨酸（LRR）的重复序列是20-30个氨基酸基序，形成疏水性/马蹄形褶皱，允许其在紧密堆积的核心内容纳多个亮氨酸残基。所有的LRR重复包含可变片段和高度保守的片段，后者占整个LRR基序的11或12个残基。ILR2（富含亮氨酸重复序列2的免疫球蛋白超家族），也称为LIX（富含亮氨酸重复结构域和含有免疫球蛋白结构域的轴突延伸蛋白），是745个氨基酸的单程膜蛋白，含有五个LRR重复序列，一个Ig样（免疫球蛋白样）结构域。一个LRRCT域和一个LRRNT域。ISLR2作为一个同质终体存在，在神经发育过程中轴突延伸是必不可少的。编码ISLR2的基因定位于人类染色体15q24.1。