GABBR1 (Human) Recombinant Protein (Q01)
产品名称: GABBR1 (Human) Recombinant Protein (Q01)
英文名称: GABBR1 (Human) Recombinant Protein (Q01)
产品编号: H00002550-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GABBR1 partial ORF ( AAH50532, 52 a.a. - 151 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- AVYIGALFPMSGGWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYG
- Theoretical MW (kDa):
- 36.63
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
- Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2550
- GeneBank Accession#:
- BC050532
- Protein Accession#:
- AAH50532
- Gene Name:
- GABBR1
- Gene Alias:
- FLJ92613,GABAB(1e),GABABR1,GABBR1-3,GPRC3A,dJ271M21.1.1,dJ271M21.1.2,hGB1a
- Gene Description:
- gamma-aminobutyric acid (GABA) B receptor, 1
- Omim ID:
- 603540
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq
- Other Designations:
- GABA-B receptor,GABAB, subunit 1c,OTTHUMP00000029114,OTTHUMP00000029115,OTTHUMP00000029116,OTTHUMP00000109099,gamma-aminobutyric acid (GABA) B receptor 1,seven transmembrane helix receptor
- Gene Pathway
- Related Disease
- Anorexia Nervosa
- Bulimia
- Carcinoma
- Epilepsy
- Epilepsy
- Epilepsy, Absence
- Epilepsy, Temporal Lobe
- Genetic Predisposition to Disease
- Lupus Erythematosus, Systemic
- Mental Disorders
- Multiple Sclerosis
- Narcolepsy
- Narcolepsy
- Nasopharyngeal Neoplasms
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenia
- Schizophrenic Psychology
- Sclerosis