BCR FISH Probe
产品名称: BCR FISH Probe
英文名称: BCR FISH Probe
产品编号: FA0453
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Entrez GeneID:
- 613
- Gene Name:
- BCR
- Gene Alias:
- ALL,BCR-ABL1,BCR1,CML,D22S11,D22S662,FLJ16453,PHL
- Gene Description:
- breakpoint cluster region
- Gene Ontology:
- Hyperlink
- Gene Summary:
- A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- bcr-abl1 e14a3 chimeric protein
- Interactome
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Angina Pectoris, Variant
- Bipolar Disorder
- Brief Psychiatric Rating Scale
- Chromosome Breakage
- Coronary Vasospasm
- Depressive Disorder, Major
- Genetic Predisposition to Disease
- Leukemia, chronic myeloid
- Leukemia, Myelocytic, Acute
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- Leukemia, Myeloid, Chronic
- Lung Neoplasms
- Pulmonary Disease, Chronic Obstructive
- Small Cell Lung Carcinoma
- Tobacco Use Disorder
- Urinary Bladder Neoplasms
- Werner syndrome