Recombinant Human PLAU/uPA Protein, His Tag
产品名称： Recombinant Human PLAU/uPA Protein, His Tag
英文名称： Recombinant Human PLAU/uPA Protein, His Tag
产品编号： 94209ES60
产品价格： 0
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2024-12-10T13:14:19
使用范围： null
- 联系人 : 李自转
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- 邮编 : 200030
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产品描述
uPA is a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys-Pro-Gly-Arg560-Val561-Val-Gly
-Gly-Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.
产品性质
Synonyms | PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD |
Uniprot No. | P00749-1 |
Source | Recombinant Human PLAU/uPA Protein (active form) is expressed from HEK293 Cells with His tag at the C-terminal. It contains Ser21-Leu431, which consists of two chains: Long chain A (Ser21-Phe177) and chain B (Ile179-Leu 431). The long chain A is further cleaved to yield a short chain A (Lys156-Phe 177) and N-terminal fragment (Ser21-Lys155). |
Molecular Weight | The protein has a predicted MW of 47.5 kDa. Due to protein lysis and glycosylation, the protein migrates to 24-26 kDa(long chain A), 35-38 kDa(chain B) and 52-60 kDa(long chain A&chain B) based on Tris-Bis PAGE result. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity | > 95% as determined by SDS-PAGE and HPLC |
Endotoxin | < 1.0 EU per 1μg of the protein by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL` is recommended. Dissolve the lyophilized protein in distilled water. |
运输与保存方法
The products are shipped with ice pack and can be stored at TUNEology 波长可调检测卡盒-->