FABP4 polyclonal antibody
产品名称： FABP4 polyclonal antibody
英文名称： FABP4 polyclonal antibody
产品编号： PAB12276
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of FABP4.
- Immunogen:
- A synthetic peptide corresponding to amino acids at C-terminus of human FABP4.
- Sequence:
- TTIKRKREDDKLVVECVM
- Host:
- Rabbit
- Theoretical MW (kDa):
- 14.7
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- Different to the related rat sequence by two amino acids.
- Form:
- Lyophilized
- Purification:
- Affinity purification
- Storage Buffer:
- Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
- Storage Instruction:
- Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2.
Furuhashi M, Tuncman G, Gorgun CZ, Makowski L, Atsumi G, Vaillancourt E, Kono K, Babaev VR, Fazio S, Linton MF, Sulsky R, Robl JA, Parker RA, Hotamisligil GS.Nature. 2007 Jun 21;447(7147):959-65. Epub 2007 Jun 6.
- 2.
- The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation.
Shum BO, Mackay CR, Gorgun CZ, Frost MJ, Kumar RK, Hotamisligil GS, Rolph MS.J Clin Invest. 2006 Aug;116(8):2183-2192.
- 3.
- Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein.
Hotamisligil GS, Johnson RS, Distel RJ, Ellis R, Papaioannou VE, Spiegelman BM.Science. 1996 Nov 22;274(5291):1377-9.
- Application Image
- Western Blot (Tissue lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Entrez GeneID:
- 2167
- Gene Name:
- FABP4
- Gene Alias:
- A-FABP,aP2
- Gene Description:
- fatty acid binding protein 4, adipocyte
- Omim ID:
- 600434
- Gene Ontology:
- Hyperlink
- Gene Summary:
- FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq
- Other Designations:
- -
- Gene Pathway