CASP2 (Human) Recombinant Protein (P01)
产品名称： CASP2 (Human) Recombinant Protein (P01)
英文名称： CASP2 (Human) Recombinant Protein (P01)
产品编号： H00000835-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CASP2 full-length ORF ( AAH02427.2, 1 a.a. - 452 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPLCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT
- Theoretical MW (kDa):
- 77.1
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 835
- GeneBank Accession#:
- BC002427.2
- Protein Accession#:
- AAH02427.2
- Gene Name:
- CASP2
- Gene Alias:
- CASP-2,ICH-1L,ICH-1L/1S,ICH1,NEDD2
- Gene Description:
- caspase 2, apoptosis-related cysteine peptidase
- Omim ID:
- 600639
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq
- Other Designations:
- ICH-1 protease,NEDD2 apoptosis regulatory,caspase 2,neural precursor cell expressed, developmentally down-regulated 2
- Related Disease
- Adenocarcinoma
- Esophageal Neoplasms
- Gastrointestinal Stromal Tumors
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Hematologic Diseases
- Hodgkin Disease
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Multiple Sclerosis
- Neoplasm Recurrence, Local
- Neoplasms, Second Primary
- Occupational Diseases
- Prostatic Neoplasms
- Waldenstrom Macroglobulinemia
- Werner syndrome