USP9X monoclonal antibody (M01), clone 1C4
产品名称： USP9X monoclonal antibody (M01), clone 1C4
英文名称： USP9X monoclonal antibody (M01), clone 1C4
产品编号： H00008239-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant USP9X.
- Immunogen:
- USP9X (NP_068706, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MTATTRGSPVGGNDNQGQAPDGQSQPPLQQNQTSSPDSSNENSPATPPDEQGQGDAPPQLEDEEPAFPHTDLAKLDDMINRPRWVVPVLP
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Deubiquitinase USP9x Confers Radioresistance through Stabilization of Mcl-1.
Trivigno D, Essmann F, Huber SM, Rudner J.Neoplasia. 2012 Oct;14(10):893-904.
- 2.
- Mcl-1 phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B-cells.
Mazumder S, Choudhary GS, Al-Harbi S, Almasan A.Cancer Res. 2012 Apr 23.
- 3.
- The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.Hepatology (2010) DOI: 10.1002/ hep.23836
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to USP9X on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged USP9X is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 8239
- GeneBank Accession#:
- NM_021906
- Protein Accession#:
- NP_068706
- Gene Name:
- USP9X
- Gene Alias:
- DFFRX,FAF,FAM
- Gene Description:
- ubiquitin specific peptidase 9, X-linked
- Omim ID:
- 300072
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- Drosophila fat facets related, X-linked,deubiquitinating enzyme FAF-X,fat facets protein related, X-linked,ubiquitin specific peptidase 9, X-linked (fat facets-like, Drosophila),ubiquitin specific protease 9, X chromosome (fat facets-like Drosophila),ubiq