神经发育及疾病miRNA PCR芯片(Neurological Development & Disease miScript miRNA PCR Array)
产品名称: 神经发育及疾病miRNA PCR芯片(Neurological Development & Disease miScript miRNA PCR Array)
英文名称: Neurological Development & Disease miScript miRNA PCR Array
产品编号: yb172
产品价格: 4800
产品产地: null
品牌商标: null
更新时间: null
使用范围: null
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- 所在区域 : 上海
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miScript miRNA PCR Array |
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Human |
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Mouse |
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人类的神经发育与疾病miRNA PCR芯片主要用于研究在神经元发育或神经系统疾病进程中差异表达的84个 miRNA的表达。这个芯片为神经科学研究者提供了一种方便的方法来分析与神经系统的正常发展和/或精神病学和神经退行性疾病发展最相关的miRNA。某些microrna,如miR-9,促进神经发育过程,如神经发生和突触可塑性。分析病变的脑组织展示各种miRNA显著特异表达。然而,这些分析很少关注个体miRNA在特定疾病过程中的功能和机制。这个芯片的分析结果可以作为神经元分化过程的分子标记,助于了解神经障碍过程的分子作用机制。结果还对基础神经学研究有重要意义,因为发育过程失调可以导致神经系统疾病,两者都经常涉及类似的miRNA调节生物途径。每张芯片含一个对照组使得分析数据时可以用相对定量ΔΔCT方法评估逆转录效率,基因组DNA污染,和PCR效率。利用这张芯片,通过实时定量PCR,可以简易且可靠地分析神经发育相关的miRNA的表达。
PCR芯片仅用于分子生物学应用。本产品不用于疾病的诊断、预防和治疗。
提供96孔板——384 -(4 x 96)板,和100孔板
Development: miR-124-3p, miR-125b-5p, miR-132-3p, miR-134, miR-138-5p, miR-9-5p.
Autistic Disorders: miR-106b-5p, miR-128, miR-132-3p, miR-140-5p, miR-146b-5p, miR-148b-3p, miR-15a-5p, miR-15b-5p, miR-181d, miR-193b-3p, miR-212-3p, miR-27a-3p, miR-320a, miR-381-3p, miR-431-5p, miR-432-5p, miR-484, miR-539-5p, miR-652-3p, miR-7-5p, miR-93-5p, miR-95.
Schizophrenia: let-7d-5p, let-7e-5p, miR-105-5p, miR-106b-5p, miR-107, miR-126-5p, miR-128, miR-130a-3p, miR-138-5p, miR-152, miR-15a-5p, miR-15b-5p, miR-181a-5p, miR-195-5p, miR-20a-5p, miR-212-3p, miR-24-3p, miR-26b-5p, miR-27a-3p, miR-29a-3p, miR-29b-3p, miR-29c-3p, miR-302a-5p, miR-302b-5p, miR-30d-5p, miR-338-3p, miR-346, miR-381-3p, miR-409-3p, miR-455-5p, miR-484, miR-485-5p, miR-487a, miR-489, miR-499a-5p, miR-512-3p, miR-518b, miR-7-5p, miR-9-3p, miR-92a-3p.
Anxiety Disorder: miR-128, miR-485-3p, miR-509-3p.
Tourette's Syndrome: miR-24-3p.
Alzheimer's Disease: let-7b-5p, let-7c, let-7d-5p, let-7e-5p, let-7i-5p, miR-101-3p, miR-106b-5p, miR-107, miR-128, miR-139-5p, miR-146a-5p, miR-15a-5p, miR-15b-5p, miR-151a-3p, miR-181a-5p, miR-19b-3p, miR-20a-5p, miR-22-3p, miR-24-3p, miR-26b-5p, miR-27a-3p, miR-28-5p, miR-298, miR-29a-3p, miR-29b-3p, miR-29c-3p, miR-30d-5p, miR-320a, miR-328, miR-346, miR-34a-5p, miR-376b-3p, miR-433, miR-485-5p, miR-488-3p, miR-511, miR-9-5p, miR-92a-3p, miR-93-5p, miR-98-5p.
Prion Diseases: let-7b-5p, miR-128, miR-139-5p, miR-146a-5p, miR-191-5p, miR-203a, miR-320a, miR-337-3p, miR-338-3p, miR-339-5p, miR-342-3p.
Huntington's Disease: miR-124-3p, miR-132-3p, miR-135b-5p, miR-29a-3p, miR-29b-3p, miR-9-5p, miR-9-3p.
Parkinson's Disease: miR-133b, miR-433, miR-7-5p.
Spinocerebellar Ataxia 1: miR-101-3p, miR-130a-3p, miR-19b-3p