KDR (Human) Recombinant Protein
产品名称: KDR (Human) Recombinant Protein
英文名称: KDR (Human) Recombinant Protein
产品编号: P4793
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human KDR (NM_002253, 807 a.a. - 1356 a.a.) partial recombinanat protein with GST tag expressed in Sf9 cells.
- Theoretical MW (kDa):
- 87.095
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purification:
- GST-Affinity Chromatography
- Concentration:
- 0.072 ug/uL
- Activity:
- 218 pmol/ug x min
- Storage Buffer:
- In 50 mM Hepes, 100 mM NaCl, pH 7.5 (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing
- Quality Control Testing:
- 2 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 3791
- Protein Accession#:
- NM_002253
- Gene Name:
- KDR
- Gene Alias:
- CD309,FLK1,VEGFR,VEGFR2
- Gene Description:
- kinase insert domain receptor (a type III receptor tyrosine kinase)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
- Other Designations:
- soluble VEGFR2,vascular endothelial growth factor receptor 2
- Related Disease
- Adenocarcinoma
- Alzheimer Disease
- Alzheimer disease
- Angina Pectoris
- Anoxia
- Asthma
- Asthma
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Intraductal, Noninfiltrating
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Colorectal Neoplasms