MARCKS (C-term) Peptide
产品名称： MARCKS (C-term) Peptide
英文名称： MARCKS (C-term) Peptide
产品编号： P1136
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MARCKS.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human MARCKS.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers.
Rauch ME, Ferguson CG, Prestwich GD, Cafiso DS.J Biol Chem. 2002 Apr 19;277(16):14068-76. Epub 2002 Feb 1.
- 2.
- The MARCKS family of protein kinase-C substrates.
Aderem A.Biochem Soc Trans. 1995 Aug;23(3):587-91.
- 3.
- Subregional mapping of 8 single copy loci to chromosome 6 by fluorescence in situ hybridization.
Rao PH, Murty VV, Gaidano G, Hauptschein R, Dalla-Favera R, Chaganti RS.Cytogenet Cell Genet. 1994;66(4):272-3.
- Entrez GeneID:
- 4082
- Protein Accession#:
- MACS_HUMAN
- Gene Name:
- MARCKS
- Gene Alias:
- 80K-L,FLJ14368,FLJ90045,MACS,PKCSL,PRKCSL
- Gene Description:
- myristoylated alanine-rich protein kinase C substrate
- Omim ID:
- 177061
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017045,myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L),phosphomyristin
- Gene Pathway