NKX2-5 polyclonal antibody (A01)
产品名称： NKX2-5 polyclonal antibody (A01)
英文名称： NKX2-5 polyclonal antibody (A01)
产品编号： H00001482-A01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length recombinant NKX2-5.
- Immunogen:
- NKX2-5 (AAH25711, 1 a.a. ~ 324 a.a) full-length recombinant protein with GST tag.
- Sequence:
- MFPSPALTPTPFSVKDILNLEQQQRSLAAAGELSARLEATLAPSSCMLAAFKPEAYAGPEAAAPGLPELRAELGRAPSPAKCASAFPAAPAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPPPPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTAAYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Application Image
- ELISA
- Entrez GeneID:
- 1482
- GeneBank Accession#:
- BC025711
- Protein Accession#:
- AAH25711
- Gene Name:
- NKX2-5
- Gene Alias:
- CHNG5,CSX,CSX1,NKX2.5,NKX2E,NKX4-1
- Gene Description:
- NK2 transcription factor related, locus 5 (Drosophila)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development (Shiojima et al., 1995 [PubMed 7665173]). It has been demonstrated that a Drosophila homeobox-containing gene called 'tinman' is expressed in the developing dorsal vessel and in the equivalent of the vertebrate heart. Mutations in tinman result in loss of heart formation in the embryo, suggesting that tinman is essential for Drosophila heart formation. Furthermore, abundant expression of Csx, the presumptive mouse homolog of tinman, is observed only in the heart from the time of cardiac differentiation. CSX, the human homolog of murine Csx, has a homeodomain sequence identical to that of Csx and is expressed only in the heart, again suggesting that CSX plays an important role in human heart formation.[supplied by OMIM
- Other Designations:
- NK2 transcription factor homolog E,NK2 transcription factor related, locus 5,cardiac-specific homeo box,tinman paralog
- Related Disease
- Alagille Syndrome
- Arthritis, Rheumatoid
- Atrial Fibrillation
- Cardiovascular Diseases
- Chromosome Deletion
- Congenital Hypothyroidism
- Diabetes Mellitus, Type 2
- Down Syndrome
- Ductus Arteriosus, Patent
- Ebstein Anomaly
- Edema
- Genetic Predisposition to Disease
- Graves Disease
- Hand Deformities, Congenital
- Heart Block
- Heart Defects, Congenital
- Heart Septal Defects
- Heart Septal Defects, Atrial
- Heart Septal Defects, Ventricular