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上海信裕生物科技有限公司
CHAD抗体

CHAD抗体

商家询价

产品名称： CHAD抗体

英文名称： CHADAntibody

产品编号： XY12963-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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  • 邮编 : 200612
  • 所在区域 : 上海
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 CHAD抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 12963-1-AP;MCF7 cellMCF7 cells were subjected to SDS PAGE followed by western blot with 12963-1-AP(CHAD antibody) at dilution of 1:400
Positive WB detected in MCF7 cells, HeLa cells, Jurkat cells
Recommended dilution WB : 1:200-1:2000
 CHAD抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CHAD fusion protein ag4077 Full name Chondroadherin
Calculated molecular
weight		 359aa,40.5 kDa Observed molecular 
weight		 41 kDa
GenBank accession 
number		 BC036360 Gene ID (NCBI) 1101
Gene symbol CHAD Synonyms Cartilage leucine rich protein, CHAD, chondroadherin, SLRR4A
Background CHAD抗体

Chondroadherin (CHAD), also known as cartilage leucine-rich protein, is a prominent noncollagenous extracellular protein in cartilage. It was first isolated from bovine cartilage. The primary structure of CHAD shows that it belongs to the family of leucine-rich repeat (LRR) proteins. It is expressed at high levels in certain zones of cartilage and also has been detected in bone, tendon, bone marrow, and chondrosarcoma cells. CHAD promotes attachment of chondrocytes, fibroblasts, and osteoblasts, mediated via the integrin alpha2beta1. It has also been shown to bind to collagen type II and both collagen type II and chondroadherin interact with integrin alpha2beta1. Besides, CHAD may play an important role in the regulation of chondrocyte growth and proliferation. CHAD抗体

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