IL17F polyclonal antibody
产品名称： IL17F polyclonal antibody
英文名称： IL17F polyclonal antibody
产品编号： PAB16921
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against full length recombinant IL17F.
- Immunogen:
- Recombinant protein corresponding to full length human IL17F.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Lyophilized
- Storage Buffer:
- Lyophilized from 20 mM KH2PO4, 150 mM NaCl, pH 7.2
- Storage Instruction:
- Store at 4°C on dry atmosphere.
After reconstitution with 0.1 mL of deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000-1:5000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.
Starnes T, Robertson MJ, Sledge G, Kelich S, Nakshatri H, Broxmeyer HE, Hromas R.J Immunol. 2001 Oct 15;167(8):4137-40.
- 2.
- Identification of a novel cytokine, ML-1, and its expression in subjects with asthma.
Kawaguchi M, Onuchic LF, Li XD, Essayan DM, Schroeder J, Xiao HQ, Liu MC, Krishnaswamy G, Germino G, Huang SK.J Immunol. 2001 Oct 15;167(8):4430-5.
- 3.
- IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
Hymowitz SG, Filvaroff EH, Yin JP, Lee J, Cai L, Risser P, Maruoka M, Mao W, Foster J, Kelley RF, Pan G, Gurney AL, de Vos AM, Starovasnik MA.EMBO J. 2001 Oct 1;20(19):5332-41.
- Applications
- Western Blot (Recombinant protein)
- Western blot using IL17F polyclonal antibody (Cat # PAB16921) shows detection of a band ~15 kDa in size corresponding to recombinant human IL17F. After transfer, the membrane was blocked overnight with 3% BSA in TBS followed by reaction with primary antibody at a 1 : 1,000 dilution. Detection occurred using DyLight 649 conjugated anti-Rabbit IgG secondary antibody diluted 1 : 20,000 in blocking buffer. Image was captured using VersaDoc MP 4000 imaging system (Bio-Rad).
- Entrez GeneID:
- 112744
- Gene Name:
- IL17F
- Gene Alias:
- IL-17F,ML-1,ML1
- Gene Description:
- interleukin 17F
- Omim ID:
- 606496
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq
- Other Designations:
- cytokine ML-1
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Cardiovascular Diseases
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Dermatitis, Atopic
- Diabetes Mellitus, Type 2
- Dyspepsia
- Edema
- Fatigue Syndrome, Chronic
- Genetic Predisposition to Disease
- Helicobacter Infections
- Inflammation
- Inflammatory Bowel Diseases
- Myocardial Infarction
- Psoriasis