FREQ (Center) Peptide
产品名称： FREQ (Center) Peptide
英文名称： FREQ (Center) Peptide
产品编号： P0564
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of FREQ.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human FREQ.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:50-100)
Flow cytometry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Up-regulation of neuronal calcium sensor-1 (NCS-1) in the prefrontal cortex of schizophrenic and bipolar patients.
Koh PO, Undie AS, Kabbani N, Levenson R, Goldman-Rakic PS, Lidow MS.Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):313-7. Epub 2002 Dec 20.
- 2.
- The neuronal calcium sensor family of Ca2+-binding proteins.
Burgoyne RD, Weiss JL.Biochem J. 2001 Jan 1;353(Pt 1):1-12.
- 3.
- Immunocytochemical localization and crystal structure of human frequenin (neuronal calcium sensor 1).
Bourne Y, Dannenberg J, Pollmann V, Marchot P, Pongs O.J Biol Chem. 2001 Apr 13;276(15):11949-55. Epub 2000 Nov 22.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of MCF-7 cell lysate (35 ug/lane) with FREQ polyclonal antibody (Cat # PAB3601).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human breast carcinomareacted with FREQ polyclonal antibody (Cat # PAB3601), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 23413
- Protein Accession#:
- P36610
- Gene Name:
- FREQ
- Gene Alias:
- DKFZp761L1223,FLUP,NCS-1,NCS1
- Gene Description:
- frequenin homolog (Drosophila)
- Omim ID:
- 603315
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022356,frequenin homolog,frequenin-like ubiquitous protein,neuronal calcium sensor 1
- Related Disease