TNFRSF11B (Human) Recombinant Protein
产品名称： TNFRSF11B (Human) Recombinant Protein
英文名称： TNFRSF11B (Human) Recombinant Protein
产品编号： H00004982-H01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Purified TNFRSF11B (AAH30155.1 24 a.a. - 194 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.
- Transfected Cell Line:
- Human HEK293T cells
- Sequence:
- FPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNSESTQK
- Host:
- Human
- Theoretical MW (kDa):
- 24.09
- Form:
- Liquid
- Preparation Method:
- Transfection of pSuper-TNFRSF11B plasmid into HEK293T cell, and the expressed protein was purified by Strep-Tactin affinity column.
- Purification:
- Strep-Tactin affinity columns
- Concentration:
- > 10 ug/ml
- Activity:
- Not Tested
- Storage Buffer:
- 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- SDS-PAGE and Western Blot
SDS-PAGE Gel
Western Blot
- Application Image
- Western Blot
- Enzyme-linked Immunoabsorbent Assay
- SDS-PAGE
- Protein Interaction
- Entrez GeneID:
- 4982
- GeneBank Accession#:
- BC030155.1
- Protein Accession#:
- AAH30155.1
- Gene Name:
- TNFRSF11B
- Gene Alias:
- MGC29565,OCIF,OPG,TR1
- Gene Description:
- tumor necrosis factor receptor superfamily, member 11b
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq
- Other Designations:
- osteoclastogenesis inhibitory factor,osteoprotegerin
- Gene Pathway
- Related Disease
- Acute Disease
- Alveolar Bone Loss
- Alzheimer Disease
- Alzheimer disease
- Arthritis, Rheumatoid
- Asthma
- Body Weight
- Bone Diseases, Metabolic
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Chronic Disease
- Coronary Disease
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Diabetic Neuropathies
- Diarrhea
- Disease Progression