PKLR (Human) Recombinant Protein (Q01)
产品名称： PKLR (Human) Recombinant Protein (Q01)
英文名称： PKLR (Human) Recombinant Protein (Q01)
产品编号： H00005313-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PKLR partial ORF ( AAH25737, 485 a.a. - 574 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS
- Theoretical MW (kDa):
- 35.64
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5313
- GeneBank Accession#:
- BC025737
- Protein Accession#:
- AAH25737
- Gene Name:
- PKLR
- Gene Alias:
- PK1,PKL,PKR,PKRL,RPK
- Gene Description:
- pyruvate kinase, liver and RBC
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- R-type/L-type pyruvate kinase,pyruvate kinase 1,pyruvate kinase isozyme R/L,pyruvate kinase type L,pyruvate kinase, liver and RBC type,pyruvate kinase, liver and blood cell,red cell/liver pyruvate kinase