ATP7B monoclonal antibody (M01), clone 3E10
产品名称： ATP7B monoclonal antibody (M01), clone 3E10
英文名称： ATP7B monoclonal antibody (M01), clone 3E10
产品编号： H00000540-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ATP7B.
- Immunogen:
- ATP7B (NP_000044, 1372 a.a. ~ 1465 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- QLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.08 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Characterization of Sandwich-Cultured Hepatocytes as an In Vitro Model to Assess the Hepatobiliary Disposition of Copper.
Ansede JH, Wright MR, St Claire RL, Hart RW, Gefroh HA, Brouwer KR.Drug Metab Dispos. 2009 May;37(5):969-76. Epub 2009 Feb 23.
- Applications
- Western Blot (Tissue lysate)
- ATP7B monoclonal antibody (M01), clone 3E10. Western Blot analysis of ATP7B expression in human colon.
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged ATP7B is approximately 0.3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 540
- GeneBank Accession#:
- NM_000053
- Protein Accession#:
- NP_000044
- Gene Name:
- ATP7B
- Gene Alias:
- PWD,WC1,WD,WND
- Gene Description:
- ATPase, Cu++ transporting, beta polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq
- Other Designations:
- ATPase, Cu(2+)- transporting, beta polypeptide,OTTHUMP00000040880,Wilson disease-associated protein,copper pump 2,copper-transporting ATPase 2